After a gutsy performance that pushed Sinner to four sets, the Italian world number one ultimately proved too strong. Yet the Canadian said he would carry plenty of positives forward from Flushing Meadows.
A sluggish Carlos Alcaraz was beaten 6-7(3), 6-3, 6-4 by Alexander Zverev on the his debut at the ATP Finals on Monday to continue his end-of-year slump with a third straight defeat.
The fifth seeded German did not let up and another break confirmed the win in two hours and 40 minutes.
Second seed Aryna Sabalenka beat Japanese qualifier Moyuka Uchijima 6-2 6-2 under the roof on Court Philippe-Chatrier on Thursday to move into the French Open third round.
Jannik Sinner has withdrawn from the U.S. Open mixed doubles event, where he was going to partner Katerina Siniakova, a day after illness forced the world number one to retire five games into his Cincinnati Open final.
Spain bounced back from an opening singles defeat on Thursday to beat the Czech Republic 2-1 and reach the Davis Cup semi-finals for the first time in six years where they will face Germany, who earned their own comeback win over Argentina.
Alexander Zverev overcame late nerves to beat world number one Novak Djokovic on Saturday and set up a final showdown with Daniil Medvedev at the ATP Finals.
Summary of sports events and persons who made news on Saturday.
Zverev won in four sets at Roland-Garros to send Alcaraz packing and reach the French Open semi-finals for a second straight year.
Alcaraz grinds down Zverev to win maiden French Open title
The German picked up two ATP titles in Cologne and also made the final of the ATP Masters 1000 event in Paris in an encouraging close to the season.
Factbox on Italy's Jannik Sinner, who beat Germany's Alexander Zverev 6-3, 7-6(4), 6-3 in the Australian Open final
World number two Carlos Alcaraz beat seventh seed Arthur Fils 6-2, 6-4 on Saturday to advance into his third Barcelona Open final, where the Spaniard will face Denmark's Holger Rune for the title.
Jannik Sinner and Carlos Alcaraz are among the world's top players calling for the Davis Cup to return to its traditional home-and-away format and be staged over two years, a proposal backed by ATP chairman Andrea Gaudenzi.
Earlier in the day, Croatia's Borna Coric said he has tested positive for coronavirus. He became the second player to test positive for COVID-19 after Bulgaria's Grigor Dimitrov.
Debutant Stefanos Tsitsipas crushed defending champion Alexander Zverev 6-3, 6-2 on Wednesday to book his place in the last four of the ATP Finals with a match to spare.
Alcaraz off to winning start at ATP Finals with win over De Minaur
The 21-year-old German became only the fifth active player to win at least three Masters 1000 titles -- joining the 'big four' of Rafael Nadal, Roger Federer, Novak Djokovic and Andy Murray.
Alexander Zverev received a suspended eight-week ban for smashing his racket against the umpire's chair at last month's ATP 500 event in Acapulco, for which he was expelled from the tournament.
Jannik Sinner kept alive his dream of becoming the first Italian to lift three Grand Slam singles trophies.
Jannik Sinner's stupendous year may have been clouded by an anti-doping controversy but on the court he is finishing the season like an express train and has won 25 of his last 26 matches.
Shelton was broken in the opening and closing games of the first set, unable to take advantage of a break point at 2-1 down while Sinner was always capable of pulling out an ace at the crucial time, hitting two in that fourth game to hold serve.
German youngster Alexander Zverev pulled off the biggest win of his career on Sunday when he beat world number two Novak Djokovic 6-4, 6-3 to win the Italian Open on Sunday.
Kazahk Bublik powers past Zverev in straight sets to reach Halle final
Alexander Zverev got the better of older brother Mischa at the Citi Open in Washington on Thursday, winning their first meeting at an ATP Tour event 6-3, 7-5.
Zverev's brother Mischa Zverev was also eliminated, going out 6-3, 6-1 to David Ferrer in the first round, while Kei Nishikori eased to a 7-5, 6-2 win over Taylor Fritz to secure a place in the third round.
The following are five contenders for the men's title at Wimbledon, which begins on Monday.
Nadal was the favourite and top seed having lifted the Barcelona Open trophy last month but played below par on a sweltering spring day.
Alexander Zverev continued to rebuild his confidence on clay with a straight sets win over Spain's Roberto Bautista Agut in the Monte Carlo Masters second round.
Chilean 21st seed Nicolas Jarry outclassed American Tommy Paul 6-3, 6-7(3), 6-3 to reach the Italian Open on Friday as former champion Alexander Zverev recovered from a slow start to beat Chilean Alejandro Tabilo 1-6, 7-6(4), 6-2.
IMAGES from Day 2 of the Wimbledon Championships, at the All England Lawn Tennis and Croquet Club, London, on Tuesday.
World No. 1 Jannik Sinner stayed cool to reach the second round of Wimbledon while several of his fellow seeds including Italian compatriot Lorenzo Musetti crashed and burned on a sizzling Tuesday.
IMAGES from the Australian Open Men's semi-finals played on Friday.
Defending champion Jannik Sinner, who has been recovering from illness, received a more favourable route to the US Open final than Carlos Alcaraz while Aryna Sabalenka will be tested in her bid to retain her title after the draw was made on Thursday.
German teenager Alexander Zverev won his first ATP Tour singles title with a 6-2, 3-6, 7-5 upset win over Switzerland's world number three Stan Wawrinka at the St Petersburg Open on Sunday.
Novak Djokovic and Carlos Alcaraz clash in the Australian Open final with history on the line as Djokovic chases a record 25th Slam and Alcaraz eyes a career Grand Slam.
Carlos Alcaraz failed to reach the Paris Masters quarter-finals after a thrilling 6-1, 3-6, 7-5 defeat to local favourite Ugo Humbert
Top seed Alexander Zverev bagged his first ATP crown of the year after beating Canada's Felix Auger-Aliassime 6-3, 6-3 to lift the bett1HULKS Indoor title in Cologne on Sunday.
Jannik Sinner began his bid to retain the ATP Finals title with a resounding 7-5, 6-1 win over injury-hit Canadian Felix Auger-Aliassime in their round-robin clash.
Germany complete comeback to beat Poland and lift United Cup